Glutathione is among the most desired and required nutrients of the body. Structurally, it is a joint of three vital amino acids i.e. glycine, cysteine and glutamic acid. It is naturally produced by the liver and neurons. Its destruction in the digestive juices is inevitable. So, uncoated oral form intake is futile. This is because strong digestive juices lead to GSH breakage into its constituent amino acids i.e. glutamate, glycine and L-cystine subsequently. The only solution to this obstacle in glutathione delivery is to coat the nutrient and then deliver it in the bloodstream. The liposomal wrapping of GSH by Liposome Encapsulation Therapy (a patented technology) [Fig. 3] can prove to be a boon. The liposomes can transport the GSH fully intact from right from saliva to cell cytoplasm. It can overcome following issues very efficiently:
Degradation of glutathione in digestive juices
Discomfort and time consumption linked to intravenous glutathione
Its deficiency may lead to various diseases.
Fig 1. (Source: https://www.sott.net/image/s19/388105/full/Low_Glutathione_Graphic.jpg)
Certain therapeutic benefits of Liposomal Glutathione Supplements are discussed below:
Highly potent antioxidant
It is said to be the master antioxidant and has the capability to charge up the other antioxidants also. But the ageing leads to decrease in its production. Therefore, oxidative stress on cells keeps on increasing and its natural body production fails to meet the increasing demand. By supplementing this powerful antioxidant, one can revive his/her standards of healthy living by alleviating the oxidative stress.
Enhances the optimum liver functioning
Liver functioning and the Glutathione (GSH) performance are interrelated. GSH is produced by the liver and in turn it maintains the substantial health and optimum functioning of the liver by removing detrimental agents from the body. In addition to it, if GSH production is reduced, it may lead to large scale liver damage at the cellular level. This is why GSH supplementation becomes necessary when the person ages in order to protect the liver.
Pours radiance and youth to your skin
The use of Glutathione for skin can reap very overwhelming results. GSH causes the suppression of melanin synthesis in case of hyperpigmentation. According to a recent study based on clinical trials, by lightening dark spots and preventing skin wrinkling it offers brightened and more youthful skin Moreover, it also provides protection from UV damage.
Liposome Encapsulation Technology is a very unique, novel and advanced technology where the medical curatives like drugs or nutrient supplements are transported to the target tissues without affecting rest of the body parts by using fat bubbles (liposomes) formed by phospholipid’s specific arrangement.
Liposomes are the transport buses which provide the required nutrients to the smallest units of the body i.e. cells. These vacuolar microscopic structures are enclosed within the selectively permeable phospholipid bilayer. These phospholipids are head and tail structures arranged in an amazing pattern which allows the safe delivery of liposomal constituents to the target cells. These are actually fat bubbles. This cell transportation mechanism is the basis of the Liposome Encapsulation Technology. Consequently, the absorption, assimilation and bioavailability of the specific nutrient or supplement are maximized tremendously by outsmarting absorption barriers of the body.
Liposomes have bilayer membranes resembling that of the target cell’s cell membrane by possessing similar phospholipid arrangement. These phospholipids have hydrophilic heads (water loving) and hydrophobic (water hating) fatty acid tails. The heads/tail later on conjugates with the hydrophilic/hydrophobic part of plasma membrane phospholipids of target cells depending upon the nature of medium. When the medium is water based, the hydrophilic i.e. water loving heads move outwards and the hydrophobic i.e. water hating fatty acid tails move inwards maintaining the bilayer integrity and vice versa when the medium is fat soluble.
Fig.:1 (Source: https://www.lunicolaboratory.com/liposomes/)
If the person is consuming the liposome encapsulated preparations, then these liposomes get absorbed into the bloodstream from the small intestine and reach to the destination cells preventing much gastric distress. After reaching target cells, they empty their ingredients directly into the intracellular fluid i.e. cytoplasm. That’s why the bioavailability of the liposomal supplements is better than the oral pills.
Lypo-Spheric Glutathione over Regular Glutathione |
||
S.No. |
Lypo-Spheric Glutathione |
Regular Glutathione |
1 |
Enclosed in Lipid spheres and remain intact in any kind of gut medium |
Not enclosed in Lipid spheres and are destroyed in gut medium |
2 |
Shows escalated absorption (up to 95%) |
Shows poor absorption (only up to 20%) and excreted out prior to absorption |
3 |
Dissolve only in blood stream and can substitute Intravenous Glutathione for high doses |
Is water soluble and reaches the bloodstream in very less amount. So, it cannot substitute Intravenous Glutathione for high doses |
4 |
Also supplies essential phospholipids required for cell repair |
Unable to supply essential phospholipids |
5 |
Prevents Glutathione exposure to atmospheric oxygen for oxidation and nutrient deterioration |
Exposes to Glutathione to atmospheric oxygen for oxidation and deterioration |
Tear packet at the notches
Squeeze the entire contents of the Liposomal Glutathione Supplement packet into 1–3 oz. of a cool beverage
Swallow in one gulp like a shot
Do not mix the Lypo-Spheric® Glutathione with hot beverages or in a blender as this could damage the liposomes.
Take one packet of Lypo-Spheric® Glutathione 1 to 2 times per day or as directed by a healthcare practitioner.
It is recommended to use Lypo-Spheric® Glutathione for a minimum 3 months for best results.
Store at room temperature.
Do not freeze or place the product in direct sunlight for extended periods of time.
If you open a packet and do not consume all of it at once, then place the packet in an airtight bag or plastic wrap and refrigerate it for up to 24 hours.
The study “Physicochemical Characteristics of Liposomal Formulations of Doctor's Formulas' Food Supplements in Biorelevant Dispersion Media” proves that liposomal vitamin and food supplementation preserves the active states of the enclosed nutrients and prevents them from getting oxidised. Moreover, such preparations do not allow the degradation of the vitamin in the acidic pH and enhance the nutrient absorption and bioavailability. Available from:
https://www.ingentaconnect.com/contentone/asp/asem/2017/00000009/00000008/art00005
The study “Research progress on liposomes: Application in food, digestion behavior and absorption mechanism” proves that Liposomal technique can control the optimum release of bio-active molecules i n the target area along with enhanced molecular stability and absorption. Available from:
https://www.sciencedirect.com/science/article/abs/pii/S0924224420305707